Description

2-(Benzyloxy)-3-Bromopyridine is a high-purity brominated pyridine derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual functional groups, which allow for selective cross-coupling reactions and further functionalization, enabling the construction of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in homogeneous catalysis and material science.
• Organic Electronic Materials: Employed in the research of organic semiconductors and light-emitting materials due to its modifiable aromatic structure.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.
• Chemical Research & Development: A versatile building block for medicinal chemistry and process chemistry in both academic and industrial R&D settings.

Basic Information

Item	Details
Product Name	2-(Benzyloxy)-3-Bromopyridine
CAS No.	52200-49-4
Molecular Formula	C₁₂H₁₀BrNO
Molecular Weight	264.12 g/mol
Synonyms	3-Bromo-2-(phenylmethoxy)pyridine; 3-Bromo-2-benzyloxypyridine; 2-Benzyloxy-3-bromopyridine; 3-Bromopyridin-2-yl benzyl ether; Pyridine, 3-bromo-2-(phenylmethoxy)-; (3-Bromo-2-pyridinyloxy)methyl]benzene
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-3-Bromopyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.