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3-Bromo-2-Chloropyridine CAS NO 52200-48-3
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CAS No.:52200-48-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Bromo-2-Chloropyridine is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity profile, enabling the construction of complex molecular architectures. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel materials.
Application
- Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
- Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides.
- Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
- Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials.
- Cross-Coupling Reactions: An effective substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl and heterobiaryl structures.
- Chemical Biology Probes: Used to develop molecular probes and tags for studying biological systems.
Basic Information
| Product Name | 3-Bromo-2-Chloropyridine |
| CAS No. | 52200-48-3 |
| Molecular Formula | C5H3BrClN |
| Molecular Weight | 192.44 g/mol |
| Synonyms | 2-Chloro-3-bromopyridine; 3-Bromo-2-chloropyridine; 2-Chloro-3-bromo-pyridine; Pyridine, 3-bromo-2-chloro-; 3-Bromo-2-chloro-pyridine; 3-Br-2-Cl-Pyridine |
| EINECS | Contact for details |
Quality Control
Our 3-Bromo-2-Chloropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder or solid |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥98.0% |
| Melting Point | Contact for details |
| Related Substances (HPLC) | Total impurities ≤2.0% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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