Description

Cyclopropanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, trans-(-)- is a high-purity, chiral cyclopropane derivative valued for its unique three-membered ring structure and stereochemical integrity. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in asymmetric synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anti-inflammatory, or central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used as a building block for creating novel pesticides, herbicides, or fungicides with enhanced efficacy and stereoselectivity.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor for chiral ligands or catalysts used in enantioselective transformations.
• Fragrance & Flavor Chemistry: Potential intermediate for synthesizing complex aroma molecules that leverage the strained cyclopropane ring for unique olfactory properties.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with specific mechanical or thermal properties.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic synthesis, particularly in cyclopropanation and stereochemistry research.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, trans-(-)-
CAS No.	52148-73-9
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	trans-(-)-2-Isopropenyl-1-cyclopropanecarboxylic acid methyl ester; Methyl trans-(-)-2-isopropenylcyclopropanecarboxylate; (-)-trans-2-Isopropenylcyclopropanecarboxylic acid methyl ester; (1R,2S)-2-(1-Methylethenyl)cyclopropanecarboxylic acid methyl ester; (1R,2S)-2-Isopropenylcyclopropanecarboxylic acid methyl ester; Methyl (1R,2S)-2-isopropenylcyclopropanecarboxylate; trans-2-Isopropenylcyclopropanecarboxylic Acid Methyl Ester, (-)-
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxylic Acid, 2-(1-Methylethenyl)-, Methyl Ester, trans-(-)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity (enantiomeric excess) and chemical purity assays, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.