Description

2-Bromo-4-Nitropyridine 1-Oxide is a versatile and highly functionalized heterocyclic building block. This compound is critical for researchers and manufacturers requiring precise bromination and nitration sites on a pyridine N-oxide scaffold for advanced synthesis. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging its reactive halogen and nitro groups.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-based ligands used in transition metal catalysis.
• Material Science Research: Employed in the development of organic electronic materials and photoactive compounds.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and process development.

Basic Information

Product Name	2-Bromo-4-Nitropyridine 1-Oxide
CAS No.	52092-43-0
Molecular Formula	C5H3BrN2O3
Molecular Weight	218.99 g/mol
Synonyms	2-Bromo-4-nitropyridine N-oxide; 4-Nitro-2-bromopyridine 1-oxide; 2-Bromo-4-nitropyridine 1-oxide; Pyridine, 2-bromo-4-nitro-, 1-oxide; 2-Bromo-4-nitropyridine N-oxide; 52092-43-0; 2-Br-4-NO2-Pyridine N-oxide
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Nitropyridine 1-Oxide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical applications. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and physical properties is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and tendency for oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.