Description

Diethyl Trimethylsilylphosphate is a specialized organosilicon phosphate ester, a key reagent in modern synthetic chemistry. Its primary value lies in its role as a versatile silylating and phosphorylating agent, enabling critical transformations in complex molecule assembly. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where precise control over molecular structure is paramount.

Application

• Pharmaceutical Intermediate Synthesis: Used as a key reagent in the preparation of nucleoside analogs, prodrugs, and other active pharmaceutical ingredients (APIs).
• Agrochemical Production: Employed in the synthesis of novel phosphate and phosphonate-based pesticides and herbicides.
• Polymer Modification: Acts as a functional monomer or cross-linking agent in the development of specialty silicones and flame-retardant polymers.
• Chemical Derivatization: Utilized in analytical chemistry for the silylation of sensitive compounds to improve their volatility for GC-MS analysis.
• Ligand and Catalyst Development: Serves as a precursor for creating novel phosphorus-containing ligands used in homogeneous catalysis.
• Surface Treatment Agent: Applied to modify material surfaces to impart specific hydrophobic or adhesion properties.

Basic Information

Product Name	Diethyl Trimethylsilylphosphate
CAS No.	52057-48-4
Molecular Formula	C7H19O4PSi
Molecular Weight	226.29 g/mol
Synonyms	Diethyl (trimethylsilyl) phosphate; Phosphoric acid, diethyl trimethylsilyl ester; Trimethylsilyl diethyl phosphate; Diethyl O-(trimethylsilyl) phosphate; O-Trimethylsilyl diethyl phosphate; Diethyl trimethylsilyl phosphate; (Trimethylsilyl)diethyl phosphate
EINECS	Contact for details

Quality Control

Our Diethyl Trimethylsilylphosphate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and industrial applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of our global customer base in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.