Description

2-Bromo-1,3,2-Benzodioxaborole is a specialized organoboron reagent featuring a reactive bromine substituent on a cyclic benzodioxaborole scaffold. This compound is valued for its role as a versatile synthetic intermediate, enabling efficient cross-coupling and functional group transformations in complex molecule assembly. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for boron-containing drug candidates.
• Suzuki-Miyaura Cross-Coupling: Serves as an electrophilic partner in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Useful for creating boron-based probes and inhibitors for studying enzymatic activity and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	2-Bromo-1,3,2-Benzodioxaborole
CAS No.	51901-85-0
Molecular Formula	C6H4BBrO2
Molecular Weight	198.81 g/mol
Synonyms	2-Bromobenzo[d][1,3,2]dioxaborole; 2-Bromo-1,3,2-benzodioxaborole; Benzo-1,3,2-dioxaborole, 2-bromo-; 2-Bromobenzodioxaborole; 2-Bromo-2H-1,3,2-benzodioxaborole; 2-Bromobenzo-1,3,2-dioxaborolane; 51901-85-0
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,3,2-Benzodioxaborole is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.