Description

2-Methyl-1,3,2-Dioxaborinane is a versatile cyclic boronic ester, a key intermediate in modern synthetic chemistry. Its primary value lies in its role as a protected boronic acid derivative, offering enhanced stability and handling characteristics compared to its free acid form. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for Suzuki-Miyaura cross-coupling reactions and other advanced organic syntheses.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides that require specific boronic ester functionalities.
• Polymer & Materials Science: Serves as a monomer or cross-linking agent in the development of novel polymeric materials, including boron-containing polymers.
• Organic Synthesis Reagent: Acts as a stable source of the boronate moiety in multi-step synthetic routes for complex organic molecules.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Research & Development: A valuable tool for medicinal chemistry and chemical biology research in academic and industrial R&D laboratories.

Basic Information

Product Name	2-Methyl-1,3,2-Dioxaborinane
CAS No.	51901-48-5
Molecular Formula	C4H9BO2
Molecular Weight	99.92 g/mol
Synonyms	2-Methyl-1,3,2-dioxaborinane; 2-Methyl-2H-1,3,2-dioxaborinane; 2-Methyl-1,3,2-dioxaborinane, 4,5-dihydro-; 4,5-Dihydro-2-methyl-1,3,2-dioxaborinane; 2-Methyl-2-oxa-1,3-diborolane; 1,3,2-Dioxaborinane, 2-methyl-; Propylene boronic ester; 2-Methyl-1,3,2-dioxaborolane (common misnomer)
EINECS	Contact for details

Quality Control

Our 2-Methyl-1,3,2-Dioxaborinane is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.