Description

(-)-1,5-Acenaphthenedicarboxylic Acid Dimethyl Ester is a high-purity, chiral organic compound belonging to the class of acenaphthene derivatives. This specific enantiomer is a critical chiral building block and intermediate in advanced organic synthesis, valued for its defined stereochemistry and rigid polycyclic structure. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and materials science sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in developing novel, enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for bioactivity and environmental safety.
• Ligand Synthesis: Acts as a starting material for creating chiral ligands used in asymmetric catalysis, such as for hydrogenation or cross-coupling reactions.
• Advanced Material Development: Employed in the research of organic semiconductors, liquid crystals, and photonic materials due to its acenaphthene-based conjugated system.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including studies on stereoselective synthesis and cycloaddition reactions.

Basic Information

Product Name	(-)-1,5-Acenaphthenedicarboxylic Acid Dimethyl Ester
CAS No.	51870-00-9
Molecular Formula	C₁₈H₁₆O₄
Molecular Weight	296.32 g/mol
Synonyms	Dimethyl (-)-1,5-Acenaphthenedicarboxylate; (1S)-1,5-Acenaphthenedicarboxylic Acid Dimethyl Ester; (-)-Dimethyl Acenaphthene-1,5-dicarboxylate; 1,5-Acenaphthenedicarboxylic acid, dimethyl ester, (-)-; Acenaphthene-1,5-dicarboxylic Acid Dimethyl Ester (enantiomer); 1,5-Bis(methoxycarbonyl)acenaphthene (specific enantiomer)
EINECS	Contact for details

Quality Control

Our (-)-1,5-Acenaphthenedicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/Chiral Column), to ensure high enantiomeric excess (e.e.) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.