Description

3-(4-Formylphenyl)-2-Propenoic Acid Ethyl Ester is a versatile aromatic α,β-unsaturated ester derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a formyl group and an activated alkene, makes it a valuable precursor for constructing complex heterocyclic and pharmaceutical intermediates. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce functionalized cinnamate motifs into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those containing chalcone, flavone, or other privileged heterocyclic scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the development of novel active ingredients for crop protection, leveraging its reactivity to create compounds with herbicidal or insecticidal properties.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for the preparation of electron-transporting or emissive layer materials in electronic displays and lighting.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including UV absorbers, optical brighteners, and perfumery chemicals.
• Cross-Coupling Reactions: Acts as a substrate in Heck, Suzuki, and other palladium-catalyzed cross-coupling reactions to form complex biaryl systems.
• Polymer Chemistry: Can be used as a monomer or co-monomer for the synthesis of functional polymers with specific optical or electronic properties.

Basic Information

Product Name	3-(4-Formylphenyl)-2-Propenoic Acid Ethyl Ester
CAS No.	51828-89-8
Molecular Formula	C₁₂H₁₂O₃
Molecular Weight	204.22 g/mol
Synonyms	Ethyl 4-Formylcinnamate; Ethyl (E)-3-(4-Formylphenyl)acrylate; 4-Formylcinnamic Acid Ethyl Ester; (E)-Ethyl 3-(4-formylphenyl)acrylate; p-Formylcinnamic Acid Ethyl Ester; Ethyl p-Formylcinnamate; 3-(4-Carboxaldehydephenyl)-2-propenoic Acid Ethyl Ester; 4-Carboxyaldehydecinnamic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 3-(4-Formylphenyl)-2-Propenoic Acid Ethyl Ester is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.