Description

2'-O-Methylisoliquiritigenin is a bioactive flavonoid derivative, specifically a methylated form of isoliquiritigenin. This compound is valued for its role as a key intermediate in pharmaceutical research and as a reference standard for analytical studies. It is primarily sought by research institutions and manufacturers in the pharmaceutical, nutraceutical, and cosmetic industries for developing therapeutic agents and high-purity ingredients.

Application

• Pharmaceutical Research: Serves as a critical intermediate or reference standard in the development of anti-inflammatory, antioxidant, and chemopreventive drug candidates.
• Analytical Chemistry: Used as a high-purity certified reference material (CRM) for method development, validation, and quality control in HPLC and LC-MS analyses.
• Nutraceutical Development: Investigated as a potential active ingredient in dietary supplements targeting oxidative stress and metabolic health.
• Cosmetic Science: Explored for inclusion in advanced skincare formulations for its potential antioxidant and skin-brightening properties.
• Biochemical Studies: Utilized in vitro and in vivo studies to investigate cellular signaling pathways, enzyme inhibition, and biological activity mechanisms.
• Academic Research: A key compound for universities and research labs studying the structure-activity relationships of flavonoids.

Basic Information

Product Name	2'-O-Methylisoliquiritigenin
CAS No.	51828-10-5
Molecular Formula	C16H14O4
Molecular Weight	270.28 g/mol
Synonyms	2'-O-Methylisoliquiritigenin; 4,2',4'-Trihydroxy-3'-methoxychalcone; 3'-Methoxy-4,2',4'-trihydroxychalcone; 2'-Methoxyisoliquiritigenin; Licochalcone B; (E)-1-(2,4-Dihydroxyphenyl)-3-(4-hydroxy-2-methoxyphenyl)prop-2-en-1-one; 2'-O-Methyl Isoliquiritigenin
EINECS	Contact for details

Quality Control

Our 2'-O-Methylisoliquiritigenin is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.