Description

Trifluoromethanesulfinic Acid Trimethylsilyl Ester is a versatile organosilicon reagent primarily used as a key building block for introducing the trifluoromethanesulfinyl group. This compound is valued for its role as a precursor and intermediate in advanced synthetic chemistry, enabling the creation of complex molecules with tailored properties. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring the trifluoromethanesulfinyl moiety.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine enhances biological activity.
• Material Science: Serves as a precursor for modifying polymer surfaces and creating specialty materials with specific surface energies.
• Organic Synthesis Reagent: Employed as a silylating agent and a protected form of trifluoromethanesulfinic acid in various nucleophilic and electrophilic reactions.
• Ligand and Catalyst Development: Useful in the preparation of novel ligands and organometallic catalysts for asymmetric synthesis.
• Fluorine Chemistry Research: A critical reagent for academic and industrial research focused on developing new fluorination methodologies and fluorinated compounds.

Basic Information

Product Name	Trifluoromethanesulfinic Acid Trimethylsilyl Ester
CAS No.	51735-75-2
Molecular Formula	C4H9F3O2SSi
Molecular Weight	206.26 g/mol
Synonyms	Trimethylsilyl Trifluoromethanesulfinate; (Trimethylsilyloxy)(trifluoromethyl)sulfane; Trifluoromethanesulfinic Acid TMS Ester; TMS Triflate; Trimethylsilyl Triflate; TMSOTf (Note: Often confused with trifluoromethanesulfonic acid trimethylsilyl ester); S-(Trifluoromethyl) Trimethylsilyl Sulfinate
EINECS	Contact for details

Quality Control

Our Trifluoromethanesulfinic Acid Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.