Description

4-Estren-17-α-Ethynyl-6-Beta, 17-β-Diol-3-One is a high-purity synthetic steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of more complex steroidal molecules with targeted biological activity. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and metabolic disease research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of steroidal active pharmaceutical ingredients (APIs) and novel drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new therapeutic compounds.
• Endocrinology Research: Serves as a starting material for compounds targeting hormone receptors and metabolic pathways.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for steroidal pharmaceuticals.

Basic Information

Product Name	4-Estren-17-α-Ethynyl-6-Beta, 17-β-Diol-3-One
CAS No.	51724-44-8
Molecular Formula	C21H28O3
Molecular Weight	328.45 g/mol
Synonyms	17α-Ethynyl-6β,17β-dihydroxy-4-estren-3-one; 17α-Ethynyl-6β,17β-dihydroxyestr-4-en-3-one; 6β,17β-Dihydroxy-17α-ethynylestr-4-en-3-one; 17α-Ethynyl-6β,17β-dihydroxy-19-norandrost-4-en-3-one; 17α-Ethynyl-6β,17β-dihydroxy-19-nortestosterone derivative
EINECS	Contact for details

Quality Control

Our 4-Estren-17-α-Ethynyl-6-Beta, 17-β-Diol-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.