Description

(4-Methoxy-Phenyl)-Propynoic Acid Ethyl Ester is a high-purity organic building block featuring a propiolate ester moiety attached to a para-methoxyphenyl ring. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, including kinase inhibitors and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and plant growth regulators.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers and advanced organic electronic materials.
• Cross-Coupling Reactions: An effective substrate in Sonogashira, Heck, and other palladium-catalyzed coupling reactions to form conjugated systems.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	(4-Methoxy-Phenyl)-Propynoic Acid Ethyl Ester
CAS No.	51718-85-5
Molecular Formula	C₁₂H₁₂O₃
Molecular Weight	204.22 g/mol
Synonyms	Ethyl 3-(4-methoxyphenyl)propiolate; 4-Methoxyphenylpropiolic Acid Ethyl Ester; Ethyl (4-Methoxyphenyl)propiolate; p-Methoxyphenylpropiolic Acid Ethyl Ester; Ethyl p-Methoxyphenylpropiolate; 3-(4-Methoxyphenyl)prop-2-ynoic Acid Ethyl Ester; Ethyl 4-Methoxyphenylpropiolate
EINECS	Contact for details

Quality Control

Every batch of (4-Methoxy-Phenyl)-Propynoic Acid Ethyl Ester is produced and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.