Description

(6R,7R,8R,13As)-5,6,7,8-Tetrahydro-1,2,3,13-Tetramethoxy-6,7-Dimethylbenzo[3,4]Cycloocta[1,2-F][1,3]Benzodioxol-8-Ol CAS NO 51670-42-9 is a complex, high-purity lignan derivative with a defined stereochemistry. This compound serves as a critical intermediate and reference standard in advanced pharmaceutical research and development. It is primarily required by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Reference Standard: Used for analytical method development, validation, and quality control (QC/QA) in pharmaceutical manufacturing.
• Biochemical Research: Investigation of biological pathways and enzyme interactions due to its specific stereochemical configuration.
• Natural Product Synthesis: Serves as a synthetic target or intermediate in the total synthesis of complex natural products with lignan backbones.
• Process Chemistry Development: Utilized in scaling up synthetic routes and optimizing catalytic processes for stereoselective synthesis.

Basic Information

Item	Details
Product Name	(6R,7R,8R,13As)-5,6,7,8-Tetrahydro-1,2,3,13-Tetramethoxy-6,7-Dimethylbenzo[3,4]Cycloocta[1,2-F][1,3]Benzodioxol-8-Ol
CAS No.	51670-42-9
Molecular Formula	C23H28O7
Molecular Weight	416.47 g/mol
Synonyms	(-)-Galbelgin; Galbelgin; (6R,7R,8R,13aR)-5,6,7,8-Tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethylbenzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-8-ol; Benzo[3,4]cycloocta[1,2-f][1,3]benzodioxol-8-ol, 5,6,7,8-tetrahydro-1,2,3,13-tetramethoxy-6,7-dimethyl-, (6R,7R,8R,13aR)-; Lignan derivative Galbelgin
EINECS	Contact for details

Quality Control

Our (6R,7R,8R,13As)-5,6,7,8-Tetrahydro-1,2,3,13-Tetramethoxy-6,7-Dimethylbenzo[3,4]Cycloocta[1,2-F][1,3]Benzodioxol-8-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, Chiral HPLC) are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a desiccator or under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.