Description

2-Amino-6-Chloro-4-Picoline is a versatile halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both amino and chloro substituents on the pyridine ring, makes it an essential intermediate for constructing complex molecules with high precision. This compound is particularly valuable for pharmaceutical research and development, agrochemical manufacturing, and the synthesis of specialty dyes and pigments.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating novel nitrogen-containing ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Acts as an intermediate for synthesizing high-performance, light-fast azo dyes and complex organic pigments.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and other functional materials.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Amino-6-Chloro-4-Picoline
CAS No.	51564-92-2
Molecular Formula	C6H7ClN2
Molecular Weight	142.59 g/mol
Synonyms	6-Chloro-2-amino-4-picoline; 2-Amino-6-chloro-4-methylpyridine; 4-Methyl-6-chloro-2-aminopyridine; 6-Chloro-4-methylpyridin-2-amine; 2-Pyridinamine, 6-chloro-4-methyl-; 4-Picoline, 2-amino-6-chloro-; 2-Amino-4-methyl-6-chloropyridine
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Chloro-4-Picoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.