Description

2-Bromo-1,5-Naphthyridine is a versatile brominated heterocyclic building block essential for modern synthetic chemistry. Its core value lies in its reactive bromine substituent, which enables efficient cross-coupling reactions and functional group transformations for constructing complex molecular architectures. This high-purity intermediate is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Development: Used to construct novel active ingredients for crop protection products, including herbicides and fungicides.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form new carbon-carbon and carbon-nitrogen bonds.
• Ligand Synthesis: Employed in the preparation of specialized nitrogen-containing ligands for catalysis and coordination chemistry.
• Academic & Contract Research: A valuable reagent for methodological studies and library synthesis in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	2-Bromo-1,5-Naphthyridine
CAS No.	51532-07-1
Molecular Formula	C8H5BrN2
Molecular Weight	209.04 g/mol
Synonyms	1,5-Naphthyridine, 2-bromo-; 2-Bromo-1,5-naphthyridine; 2-Bromonaphthyridine; 2-Bromo[1,5]naphthyridine; 2-Bromo-1,5-diazanaphthalene; 2-Bromopyrido[3,2-b]pyrazine; Bromo-1,5-naphthyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,5-Naphthyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Area %)
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.