Description

[[Estra-1,3,5(10)-Triene-2,3,16α,17β-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane) is a high-purity, organosilicon-modified steroid derivative, representing a critical advanced intermediate in fine chemical synthesis. Its value lies in providing a protected, reactive scaffold that enables precise chemical transformations under controlled conditions, essential for producing complex target molecules. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and advanced materials sectors for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key protected intermediate in the multi-step synthesis of novel steroid-based drugs and hormone analogs.
• Organic Synthesis Building Block: Used in research and development for constructing complex molecular architectures, leveraging its reactive silyl ether and steroid core functionalities.
• Chemical Research & Development: Serves as a valuable reference standard and starting material in academic and industrial laboratories for methodological studies and new reaction development.
• Specialty Fine Chemical Production: Employed in the manufacture of high-value, low-volume chemicals for advanced applications in material science and biotechnology.

Basic Information

Product Name	[[Estra-1,3,5(10)-Triene-2,3,16α,17β-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane)
CAS No.	51497-46-2
Molecular Formula	C40H76O4Si4
Molecular Weight	733.4 g/mol
Synonyms	Estra-1,3,5(10)-triene-2,3,16α,17β-tetrayl tetraoxytetrakis(trimethylsilane); 2,3,16,17-Tetrakis-O-(trimethylsilyl)estradiol; Estradiol-2,3,16,17-tetrakis(trimethylsilyl) ether; Estradiol tetrakis(trimethylsilyl ether); Tetrakis-O-trimethylsilylestradiol; TMS-Estradiol derivative; 2,3,16,17-Tetra-O-TMS-Estradiol; E2-2,3,16,17-TMS
EINECS	Contact for details

Quality Control

Our [[Estra-1,3,5(10)-Triene-2,3,16α,17β-Tetryl]Tetra(Oxy)]Tetrakis(Trimethylsilane) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and traceability for research and cGMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is light-sensitive and easily oxidized; prolonged exposure to air, light, or moisture should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.