Description

(E)-1-(4-Bromophenyl)-3-(4-Methylphenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct molecular structure. This compound serves as a critical pharmaceutical intermediate and a versatile organic building block for advanced chemical synthesis. It is primarily required by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and material science sectors for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory, anticancer, and antimicrobial pathways.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and cyclization processes to construct complex heterocyclic compounds.
• Agrochemical Research: Serves as a core structure for developing new generation pesticides and herbicides with enhanced efficacy.
• Material Science: Investigated as a monomer or additive for creating specialized polymers and organic electronic materials.
• Chemical Biology Probe: Used in research to study enzyme inhibition and protein-ligand interactions due to its chalcone scaffold.
• Academic & Industrial R&D: Essential for methodological studies in organic chemistry and scale-up process development.

Basic Information

Product Name	(E)-1-(4-Bromophenyl)-3-(4-Methylphenyl)Prop-2-En-1-One
CAS No.	51477-10-2
Molecular Formula	C16H13BrO
Molecular Weight	301.18 g/mol
Synonyms	4'-Bromo-4-methylchalcone; (E)-1-(4-Bromophenyl)-3-(p-tolyl)prop-2-en-1-one; 3-(4-Methylphenyl)-1-(4-bromophenyl)-2-propen-1-one; p-Bromophenyl p-tolyl ketone, unsaturated; Chalcone, 4'-bromo-4-methyl-; 4-Methyl-4'-bromochalcone; (E)-3-(4-Methylphenyl)-1-(4-bromophenyl)prop-2-en-1-one
EINECS	Contact for details

Quality Control

Our (E)-1-(4-Bromophenyl)-3-(4-Methylphenyl)Prop-2-En-1-One is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent contamination and moisture absorption. This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.