Description

6α-Hydroxy Mestranol is a key pharmaceutical intermediate and a hydroxylated derivative of the synthetic estrogen, mestranol. This compound is of significant importance in the research and development of steroidal drugs, particularly for its role as a precursor in synthesizing more complex, biologically active molecules. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in steroid chemistry and hormone-related studies.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel steroidal drugs and hormone analogs.
• Research & Development: Used in academic and industrial research to study estrogen metabolism, structure-activity relationships (SAR), and to develop new therapeutic agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating specialized chemical libraries and advanced intermediates.

Basic Information

Item	Details
Product Name	6α-Hydroxy Mestranol
CAS No.	51414-85-8
Molecular Formula	C₂₁H₂₈O₃
Molecular Weight	328.45 g/mol
Synonyms	6α-Hydroxymestranol; 17α-Ethynyl-6α-hydroxy-3-methoxyestra-1,3,5(10)-trien-17β-ol; 6α-Hydroxy-17α-ethynyl-3-methoxyestra-1,3,5(10)-trien-17β-ol; 3-Methoxy-17α-ethynyl-6α-hydroxyestra-1,3,5(10)-trien-17β-ol; 6α-Hydroxy-17α-ethynylestradiol 3-methyl ether; Mestranol, 6α-hydroxy-
EINECS	Contact for details

Quality Control

Our 6α-Hydroxy Mestranol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to ensure traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.