Description

1-Azaspiro[3.3]heptane oxalate is a high-purity, versatile organic salt serving as a critical building block in advanced pharmaceutical synthesis. This compound is valued for its unique spirocyclic structure, which provides a rigid, three-dimensional scaffold essential for developing novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the discovery and development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a constrained amine building block to explore structure-activity relationships (SAR) and improve drug-like properties such as solubility and metabolic stability.
• Ligand and Probe Development: Employed in the creation of chemical probes for studying biological pathways and protein function.
• Agrochemical Synthesis: Potential intermediate in the development of new crop protection agents with novel modes of action.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	1-Azaspiro[3.3]heptane Oxalate
CAS No.	51392-72-4
Molecular Formula	C8H13NO5
Molecular Weight	203.19 g/mol
Synonyms	1-Azaspiro[3.3]heptane, oxalic acid salt; Azaspiro[3.3]heptane oxalate; 1-Aza-3-oxaspiro[3.3]heptane oxalate (incorrect but common); 2-Oxa-6-azaspiro[3.3]heptane oxalate; Spiro[cyclopropane-1,3'-pyrrolidine] oxalate; 1-Azaspiro[3.3]heptan-1-ium oxalate; 1-Aza-3-oxaspiro[3.3]heptane hydrogen oxalate; 1-Azaspiro[3.3]heptane hemioxalate
EINECS	Contact for details

Quality Control

Our 1-Azaspiro[3.3]heptane oxalate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.