Description

6-Phenoxynicotinoyl Chloride is a high-purity, reactive acid chloride intermediate essential for advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 6-phenoxynicotinate moiety, a key structural motif in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides containing nicotinic acid derivatives.
• Peptide Coupling Reagent: Acts as a coupling agent in peptide synthesis to form amide bonds under mild conditions.
• Material Science Research: Intermediate for creating functional polymers and liquid crystals with specific optical properties.
• Chemical Biology Probes: Utilized in the development of activity-based probes and molecular tags for proteomics.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific molecule development.

Basic Information

Product Name	6-Phenoxynicotinoyl Chloride
CAS No.	51362-51-7
Molecular Formula	C12H8ClNO2
Molecular Weight	233.65 g/mol
Synonyms	6-Phenoxynicotinic Acid Chloride; 6-Phenoxypyridine-3-carbonyl Chloride; Nicotinoyl Chloride, 6-phenoxy-; 3-Pyridinecarbonyl chloride, 6-phenoxy-; 6-Phenoxy-3-pyridinecarbonyl chloride; Phenoxynicotinoyl Chloride
EINECS	Contact for details

Quality Control

Our 6-Phenoxynicotinoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.