Description

4-Peroxycyclophosphamide is a specialized peroxy derivative of cyclophosphamide, primarily utilized as a key synthetic intermediate and research chemical. Its unique peroxy functional group makes it a valuable reagent for oxidation reactions and a compound of significant interest in pharmaceutical research and development. This product is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors engaged in advanced synthesis and investigative studies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs.
• Research & Development: Used as a model compound in biochemical and pharmacological research, particularly in studies related to oxidative metabolism and prodrug activation mechanisms.
• Organic Synthesis: Acts as a specialized oxidizing agent or building block in the synthesis of complex organic molecules and heterocyclic compounds.
• Bioconjugation Studies: Employed in the development of targeted drug delivery systems and antibody-drug conjugates (ADCs) due to its reactive peroxy group.
• Metabolite Studies: Utilized in analytical and metabolic studies to understand the pathways and effects of related chemotherapeutic agents.

Basic Information

Product Name	4-Peroxycyclophosphamide
CAS No.	51274-71-6
Molecular Formula	C7H15Cl2N2O3P
Molecular Weight	277.09 g/mol
Synonyms	4-Hydroperoxycyclophosphamide; 4-HPCPA; NSC 181815; Peroxycyclophosphamide; Cyclophosphamide 4-hydroperoxide; 4-Hydroperoxy-cyclophosphamide; 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 4-oxide 4-hydroperoxide
EINECS	Contact for details

Quality Control

Our 4-Peroxycyclophosphamide is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents. We adhere to cGMP principles where applicable to guarantee consistency, reliability, and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled temperature of -20°C or below to maintain stability. The container should be kept in a dry, well-ventilated area, away from heat, sparks, and incompatible materials such as strong reducing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Single Maximum Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.