Description

5-Chloropyridine-3-Carboxylic Acid Methyl Ester is a high-purity, versatile pyridine derivative and a key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing heterocyclic compounds and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom chemical synthesis services catering to diverse R&D projects.
• Academic and Industrial R&D: Utilized in exploratory chemistry for developing new synthetic methodologies and discovering novel chemical entities.

Basic Information

Product Name	5-Chloropyridine-3-Carboxylic Acid Methyl Ester
CAS No.	51269-81-9
Molecular Formula	C7H6ClNO2
Molecular Weight	171.58 g/mol
Synonyms	Methyl 5-chloronicotinate; 5-Chloro-3-pyridinecarboxylic acid methyl ester; Methyl 5-chloropyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 5-chloro-, methyl ester; 5-Chloronicotinic acid methyl ester; Nicotinic acid, 5-chloro-, methyl ester
EINECS	Contact for details

Quality Control

Our 5-Chloropyridine-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent quality suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.