Description

5,5-Diethyl-1-(2-Methylpropyl)-3-(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon-substituted barbiturate derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in the unique reactivity imparted by the trimethylsilyl group, which enables selective transformations and protection strategies that are difficult to achieve with other functional groups. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel barbiturate analogs and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Organosilicon Chemistry: Serves as a versatile precursor for introducing silicon functionality into complex molecules, useful in materials science.
• Chemical Synthesis: Employed as a protected or modified intermediate in multi-step organic synthesis, facilitating challenging bond formations.
• Academic & R&D: A valuable reagent for methodological studies in synthetic organic chemistry and new reaction development.

Basic Information

Product Name	5,5-Diethyl-1-(2-Methylpropyl)-3-(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	51209-92-8
Molecular Formula	C15H28N2O3Si
Molecular Weight	312.48 g/mol
Synonyms	3-(Trimethylsilyl)-5,5-diethyl-1-(2-methylpropyl)barbituric acid; 1-Isobutyl-3-(trimethylsilyl)-5,5-diethylbarbituric acid; 5,5-Diethyl-1-isobutyl-3-(trimethylsilyl)barbituric acid; TMS-Barbiturate Derivative; Silicon-containing barbiturate; 1-(2-Methylpropyl)-3-(trimethylsilyl)-5,5-diethyl-2,4,6-pyrimidinetrione
EINECS	Contact for details

Quality Control

Our production of 5,5-Diethyl-1-(2-Methylpropyl)-3-(Trimethylsilyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support custom synthesis and can tailor specifications to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.