Description

R(+)-Secobarbital Sodium is the sodium salt of the dextrorotatory enantiomer of secobarbital, a short-acting barbiturate derivative. This specific enantiomer is of significant interest in pharmaceutical research and development due to its distinct pharmacological profile compared to its racemic or levorotatory counterparts. It is primarily utilized by research institutions, pharmaceutical companies, and analytical laboratories engaged in neuroscience, pharmacokinetic studies, and the development of chiral therapeutics. The compound is supplied with a high level of purity to meet the stringent demands of advanced research applications.

Application

• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in drug manufacturing.
• Neuroscience Research: Used in preclinical studies to investigate the mechanisms of action, receptor binding, and metabolic pathways of barbiturates.
• Chiral Pharmacology Studies: Essential for studying the stereoselective effects, potency, and toxicity of individual secobarbital enantiomers.
• Forensic and Clinical Toxicology: Employed as an analytical standard for the accurate identification and quantification of secobarbital in biological samples.
• Metabolite Synthesis & Identification: Acts as a precursor or standard in the synthesis and study of secobarbital metabolites.
• Regulatory Compliance Testing: Used in laboratories to validate analytical procedures for regulatory submissions to agencies like the FDA and EMA.

Basic Information

Product Name	R(+)-Secobarbital Sodium
CAS No.	51165-36-7
Molecular Formula	C12H17N2NaO3
Molecular Weight	260.27 g/mol
Synonyms	(+)-Secobarbital Sodium; Dextro-Secobarbital Sodium; 5-Allyl-5-(1-methylbutyl)barbituric acid sodium salt (R-enantiomer); Sodium (R)-5-allyl-5-(1-methylbutyl)barbiturate; Secobarbital Sodium (R-isomer); R-(+)-Secobarbital Sodium; Quinalbarbitone Sodium (R-enantiomer); Secobarbital Sodium Salt (R-form)
EINECS	Contact for details

Quality Control

Our R(+)-Secobarbital Sodium is manufactured under controlled conditions to ensure high chemical purity and enantiomeric excess suitable for research applications. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral chromatography to confirm enantiomeric identity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.