Description

2-Hydroxy-6-Methylpyridine-3-Carboxylic Acid Ethyl Ester is a versatile pyridine derivative ester, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it a valuable precursor for the development of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its heterocyclic core for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the development of organic electronic materials and functional polymers.
• Chemical Research & Development: A versatile starting material for exploring new synthetic pathways and creating complex molecular libraries.

Basic Information

Product Name	2-Hydroxy-6-Methylpyridine-3-Carboxylic Acid Ethyl Ester
CAS No.	51146-04-4
Molecular Formula	C9H11NO3
Molecular Weight	181.19 g/mol
Synonyms	Ethyl 2-Hydroxy-6-methylnicotinate; Ethyl 2-Hydroxy-6-methyl-3-pyridinecarboxylate; 6-Methyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid ethyl ester; 2-Hydroxy-6-methylnicotinic acid ethyl ester; 3-Carbethoxy-6-methyl-2-pyridone; 2-Pyridone, 3-carbethoxy-6-methyl-; 2-Hydroxy-6-methyl-3-pyridinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-6-Methylpyridine-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.