Description

1-(tert-Butoxycarbonyl)-2,5-Dihydro-1H-Pyrrole-2-Carboxylic Acid is a high-value, protected pyrrole derivative that serves as a critical building block in advanced organic synthesis. Its primary importance lies in its role as a versatile intermediate for constructing complex nitrogen-containing heterocycles, which are core structures in numerous active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-purity intermediates for drug discovery and process scale-up.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of pyrrole-based drug candidates, including kinase inhibitors and other targeted therapies.
• Peptidomimetic Synthesis: Used to incorporate constrained, proline-like structures into peptide chains to enhance metabolic stability and biological activity.
• Agrochemical Research: Intermediate in the development of novel herbicides and fungicides containing heterocyclic scaffolds.
• Material Science Precursor: Serves as a monomer or functionalization agent for creating specialized polymers with unique electronic or binding properties.
• Academic & Contract Research: A valuable reagent for methodological development and the construction of complex natural product analogs in research laboratories.

Basic Information

Product Name	1-(tert-Butoxycarbonyl)-2,5-Dihydro-1H-Pyrrole-2-Carboxylic Acid
CAS No.	51077-13-5
Molecular Formula	C10H15NO4
Molecular Weight	213.23 g/mol
Synonyms	1-Boc-2,5-dihydro-1H-pyrrole-2-carboxylic acid; 2,5-Dihydro-1H-pyrrole-2-carboxylic acid, 1-[(1,1-dimethylethoxy)carbonyl]-; 1-N-Boc-3-pyrroline-2-carboxylic acid; 1-(tert-Butoxycarbonyl)-3-pyrroline-2-carboxylic acid; Boc-2,5-dihydropyrrole-2-COOH; 2-Carboxy-3-pyrroline-1-carboxylic acid tert-butyl ester; 1-Boc-2,3-didehydropyrrolidine-2-carboxylic acid; tert-Butyl 2-carboxy-2,5-dihydro-1H-pyrrole-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)-2,5-Dihydro-1H-Pyrrole-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for the grade. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.