Description

(3-Bromo-Pyridin-4-Yl)-Acetic Acid Ethyl Ester is a high-purity brominated pyridine derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its versatile reactivity, serving as a key intermediate for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and process development scientists engaged in the synthesis of novel active ingredients, particularly in the development of kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitor candidates and other small molecule drugs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Chemical Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and functional group transformations to introduce the 3-bromo-4-substituted pyridine moiety into more complex structures.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced organic materials, such as ligands for catalysts or components for organic electronics.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting discovery chemistry and route scouting projects.

Basic Information

Product Name	(3-Bromo-Pyridin-4-Yl)-Acetic Acid Ethyl Ester
CAS No.	51054-99-0
Molecular Formula	C9H10BrNO2
Molecular Weight	244.09 g/mol
Synonyms	Ethyl (3-bromopyridin-4-yl)acetate; 4-Pyridineacetic acid, 3-bromo-, ethyl ester; (3-Bromo-4-pyridinyl)acetic acid ethyl ester; Ethyl 2-(3-bromopyridin-4-yl)acetate; 3-Bromo-4-pyridylacetic acid ethyl ester; Ethyl (3-bromo-4-pyridyl)acetate; 51054-99-0; (3-Bromopyridin-4-yl)acetic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our (3-Bromo-Pyridin-4-Yl)-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.