Description

1-Azaspiro[3.3]heptan-2-one is a versatile and synthetically valuable spirocyclic lactam building block. This compound is a key intermediate in modern pharmaceutical and agrochemical research, prized for its rigid, three-dimensional structure that can impart unique biological activity and metabolic stability to final molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where its spirocyclic core can enhance target binding and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers and functional materials with specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	1-Azaspiro[3.3]heptan-2-one
CAS No.	51047-68-8
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	1-Azaspiro[3.3]heptan-2-one; 2-Azabicyclo[2.2.1]heptan-3-one; 1-Azonia-2-oxospiro[3.3]heptane; 1-Azaspiro[3.3]heptane-2-one; 2-Oxo-1-azaspiro[3.3]heptane; 1-Aza-2-oxospiro[3.3]heptane; Spiro[cyclopropane-1,2'-pyrrolidin]-3'-one
EINECS	Contact for details

Quality Control

Our 1-Azaspiro[3.3]heptan-2-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.