Description

5-Azabicyclo[2.1.0]pentane-5-carboxylic acid, 1-methyl-, methyl ester (9CI) is a specialized bicyclic organic compound featuring a unique strained azabicyclo[2.1.0]pentane scaffold. This structure makes it a valuable and versatile chemical building block for advanced synthetic chemistry, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing constrained nitrogen heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific three-dimensional molecular shapes for target binding.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Potential building block for advanced polymers and functional materials with unique thermal or mechanical properties.
• Academic & Contract Research: Employed in universities and CROs for methodological studies and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	5-Azabicyclo[2.1.0]pentane-5-carboxylic acid, 1-methyl-, methyl ester (9CI)
CAS No.	51047-64-4
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	1-Methyl-5-azabicyclo[2.1.0]pentane-5-carboxylic acid methyl ester; Methyl 1-methyl-5-azabicyclo[2.1.0]pentane-5-carboxylate; 5-Azabicyclo[2.1.0]pentane-5-carboxylic acid, 1-methyl-, methyl ester; 1-Methyl-5-azabicyclo[2.1.0]pentane-5-carboxylate; Azabicyclo[2.1.0]pentane derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high purity, critical for sensitive R&D and scale-up processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.