Description

2-Amino-17-Methyl-4,5α-Epoxy-7,8-Didehydromorphinan-3,6α-Diol is a high-purity synthetic opioid alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of specialized analgesics and for pharmacological studies targeting the central nervous system. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing next-generation therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway for novel opioid analgesics and antitussive agents.
• Pharmacological Research: Reference standard and active compound for in-vitro and in-vivo studies on opioid receptor binding, efficacy, and selectivity.
• Medicinal Chemistry: Core scaffold for the design, modification, and development of new chemical entities (NCEs) with potential analgesic properties.
• Analytical Standard: High-purity material used as a calibration standard in HPLC, GC-MS, and other analytical methods for quality control and forensic analysis.
• Biochemical Studies: Tool compound for investigating pain pathways, neurotransmitter systems, and the biochemical mechanisms of opioid action.

Basic Information

Product Name	2-Amino-17-Methyl-4,5α-Epoxy-7,8-Didehydromorphinan-3,6α-Diol
CAS No.	51006-03-2
Molecular Formula	C₁₇H₂₀N₂O₄
Molecular Weight	316.35 g/mol
Synonyms	17-Methyl-4,5α-epoxy-7,8-didehydromorphinan-3,6α-diol-2-amine; 2-Aminomorphinan derivative; Noroxymorphone derivative; 14-Hydroxydihydronormorphine; 2-Amino-14-hydroxy-7,8-dihydronormorphine; 2-Amino-3,6α-dihydroxy-17-methyl-4,5α-epoxy-7,8-didehydromorphinan
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-17-Methyl-4,5α-Epoxy-7,8-Didehydromorphinan-3,6α-Diol is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.