Description

Diethyl-n-Benzylideneaminomethylphosphonate is a specialized organophosphorus compound that serves as a key intermediate in advanced organic synthesis. Its primary value lies in its role as a versatile building block for the preparation of α-aminophosphonates and other pharmacologically active molecules. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of α-aminophosphonic acids and their derivatives, which are analogs of natural amino acids with potential bioactivity.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate phosphonate moieties.
• Ligand Synthesis: Serves as a starting material for creating chiral phosphonate-based ligands used in asymmetric catalysis.
• Peptidomimetics: Employed in the construction of phosphonate-containing peptide analogs for medicinal chemistry and biochemical studies.
• Material Science: A building block for functionalized polymers and flame-retardant materials.
• Chemical Biology Probes: Used to develop enzyme inhibitors and activity-based probes targeting hydrolytic enzymes.

Basic Information

Product Name	Diethyl-n-Benzylideneaminomethylphosphonate
CAS No.	50917-73-2
Molecular Formula	C₁₂H₁₈NO₃P
Molecular Weight	255.25 g/mol
Synonyms	Diethyl [(benzylideneamino)methyl]phosphonate; Diethyl (Benzylideneaminomethyl)phosphonate; N-(Diethoxyphosphinylmethyl)benzylidenimine; Benzylideneamino-methanephosphonic Acid Diethyl Ester; Phosphonic acid, P-[(benzylideneamino)methyl]-, diethyl ester; Diethyl (N-benzylideneaminomethyl)phosphonate
EINECS	Contact for details

Quality Control

Our Diethyl-n-Benzylideneaminomethylphosphonate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.