Description

5,6-Epoxy-5,6-Dihydroretinoic Acid Trimethylsilyl Ester is a key synthetic intermediate in the production of retinoids and vitamin A analogs. This compound is crucial for researchers and manufacturers requiring precise chemical modifications to the retinoic acid backbone for pharmaceutical and advanced material applications. It is primarily utilized in the development of novel therapeutic agents, particularly in dermatology and oncology research, as well as in the synthesis of specialized biochemical probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel retinoid-based drugs targeting skin conditions and cancers.
• Biochemical Research: Used as a precursor or standard in metabolic pathway studies involving vitamin A and retinoic acid signaling.
• Advanced Material Synthesis: Serves as a specialized monomer or modifier in the development of light-sensitive polymers and functional materials.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Cosmeceutical R&D: Investigated for the development of next-generation anti-aging and dermatological treatments.

Basic Information

Product Name	5,6-Epoxy-5,6-Dihydroretinoic Acid Trimethylsilyl Ester
CAS No.	50876-23-8
Molecular Formula	C23H36O3Si
Molecular Weight	388.62 g/mol
Synonyms	5,6-Epoxy-5,6-dihydroretinoic acid TMS ester; Retinoic acid, 5,6-epoxy-5,6-dihydro-, trimethylsilyl ester; Trimethylsilyl 5,6-epoxy-5,6-dihydroretinoate; TMS-5,6-epoxyretinoate; (all-E)-5,6-Epoxy-5,6-dihydroretinoic acid trimethylsilyl ester; Vitamin A acid derivative TMS ester; Retinoid TMS ether intermediate
EINECS	Contact for details

Quality Control

Our 5,6-Epoxy-5,6-Dihydroretinoic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider refrigeration at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.