Description

5-[m-(Trifluoromethyl)Benzyl]-2,4-Pyrimidinediamine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced chemical synthesis. This compound matters as a critical building block for developing novel active pharmaceutical ingredients (APIs) and agrochemicals, where its trifluoromethyl benzyl moiety offers unique physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used as a precursor in the development of advanced pesticides and herbicides, leveraging the biological activity of the pyrimidine core.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials or metal-organic frameworks (MOFs) due to its aromatic and nitrogen-rich structure.
• Biochemical Tool Compound: Can be utilized in biochemical assays to study enzyme inhibition or cellular pathways.

Basic Information

Product Name	5-[m-(Trifluoromethyl)Benzyl]-2,4-Pyrimidinediamine
CAS No.	50823-94-4
Molecular Formula	C12H11F3N4
Molecular Weight	268.24 g/mol
Synonyms	5-[(3-(Trifluoromethyl)phenyl)methyl]pyrimidine-2,4-diamine; 2,4-Diamino-5-[(3-(trifluoromethyl)phenyl)methyl]pyrimidine; 5-(3-Trifluoromethylbenzyl)-2,4-diaminopyrimidine; 5-(m-Trifluoromethylbenzyl)-2,4-pyrimidinediamine; 5-(3-(Trifluoromethyl)benzyl)pyrimidine-2,4-diamine; 50823-94-4; 5-(alpha,alpha,α-Trifluoro-m-tolyl)pyrimidine-2,4-diamine
EINECS	Contact for details

Quality Control

Our 5-[m-(Trifluoromethyl)Benzyl]-2,4-Pyrimidinediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided and available upon request, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.