Description

Chloromethyl (4-Nitrophenyl) Carbonate is a specialized organic synthesis intermediate featuring a reactive chloromethyl carbonate group and a UV-active nitrophenyl moiety. This compound matters for its role as a versatile building block in the preparation of active pharmaceutical ingredients (APIs) and advanced functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of prodrugs, carbonate-linked drug conjugates, and polymer-drug complexes.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for synthesizing specialty polycarbonates and stimuli-responsive polymers.
• Protecting Group Chemistry: Used for the selective protection of alcohols and amines in multi-step organic synthesis.
• Bioconjugation: Facilitates the covalent attachment of small molecules, dyes, or drugs to proteins, peptides, or nanoparticles.
• Material Science: Employed in the surface functionalization of materials and the development of novel coatings.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides and plant growth regulators.

Basic Information

Item	Detail
Product Name	Chloromethyl (4-Nitrophenyl) Carbonate
CAS No.	50780-50-2
Molecular Formula	C8H6ClNO5
Molecular Weight	231.59 g/mol
Synonyms	4-Nitrophenyl Chloromethyl Carbonate; (4-Nitrophenyloxy)carbonyloxymethyl Chloride; p-Nitrophenyl Chloromethyl Carbonate; Chloromethyl 4-Nitrophenyl Carbonate; Carbonochloridic Acid, (4-Nitrophenyl) Ester, Chloromethyl Ester; Chloromethyl P-Nitrophenyl Carbonate; 50780-50-2
EINECS	Contact for details

Quality Control

Our Chloromethyl (4-Nitrophenyl) Carbonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.