Description

1,2,3,4-Tetra-o-Acetyl-β-L-Fucopyranose is a key acetylated derivative of L-fucose, a deoxy sugar, serving as a crucial protected intermediate in synthetic carbohydrate chemistry. Its primary value lies in enabling the controlled synthesis of complex oligosaccharides, glycoconjugates, and fucose-containing bioactive molecules. This high-purity building block is essential for researchers and manufacturers in pharmaceutical development, glycobiology research, and the production of diagnostic reagents.

Application

• Glycoconjugate Synthesis: A vital protected intermediate for the chemical and enzymatic construction of fucosylated oligosaccharides and glycoproteins.
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutics, including anti-inflammatory, anti-cancer, and anti-metastatic agents that target fucose-mediated biological pathways.
• Glycobiology Research: Serves as a standard or starting material for studying fucosyltransferases, designing enzyme inhibitors, and probing carbohydrate-protein interactions (e.g., selectin binding).
• Diagnostic Reagent Production: Employed in the synthesis of antigens, probes, and assay components for detecting specific antibodies or carbohydrate-binding proteins.
• Chemical Biology Tools: Facilitates the creation of labeled fucose analogs (e.g., fluorescent, biotinylated) for cell surface imaging and metabolic labeling studies.
• Standard Reference Material: Provides a high-purity compound for analytical method development, quality control, and calibration in carbohydrate analysis.

Basic Information

Product Name	1,2,3,4-Tetra-o-Acetyl-β-L-Fucopyranose
CAS No.	50615-78-6
Molecular Formula	C14H20O9
Molecular Weight	332.30 g/mol
Synonyms	1,2,3,4-Tetra-O-acetyl-β-L-fucopyranose; β-L-Fucopyranose, 1,2,3,4-tetraacetate; Tetra-O-acetyl-L-fucose; L-Fucose tetraacetate; 1,2,3,4-Tetra-O-acetyl-L-fucose; 2,3,4-Tri-O-acetyl-α-L-fucopyranosyl acetate; (2R,3S,4S,5R)-2,3,4,5-Tetrakis(acetyloxy)-6-methyloxane
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetra-o-Acetyl-β-L-Fucopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.