Description

3-[1A,2,7,7A-Tetrahydro-2-Methoxy-8-Phenyl-1,2,7-Metheno-1H-Cyclopropa[B]Naphthalen-1-Yl]Pyridine is a complex, polycyclic organic compound featuring a unique bridged structure that combines naphthalene, cyclopropane, and pyridine moieties. This intricate molecular architecture makes it a valuable advanced intermediate for research and development in pharmaceutical chemistry and material science. It is primarily sought by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), specialty agrochemicals, and functional organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides due to its complex, bioactive scaffold.
• Organic Electronic Materials: Investigated as a potential precursor for charge-transport materials or emissive layers in OLEDs and other optoelectronic devices.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in organic synthesis and catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic projects.

Basic Information

Product Name	3-[1A,2,7,7A-Tetrahydro-2-Methoxy-8-Phenyl-1,2,7-Metheno-1H-Cyclopropa[B]Naphthalen-1-Yl]Pyridine
CAS No.	50559-53-0
Molecular Formula	C24H21NO
Molecular Weight	339.43 g/mol
Synonyms	1,2,7,7a-Tetrahydro-2-methoxy-8-phenyl-1,2,7-metheno-1H-cyclopropa[b]naphthalen-1-yl-3-pyridine; 3-(1a,2,7,7a-Tetrahydro-2-methoxy-8-phenyl-1,2,7-metheno-1H-cyclopropa[b]naphthalen-1-yl)pyridine; 8-Phenyl-1,2,7,7a-tetrahydro-2-methoxy-1,2,7-metheno-1H-cyclopropa[b]naphthalen-1-yl-3-pyridine; Pyridine, 3-(1a,2,7,7a-tetrahydro-2-methoxy-8-phenyl-1,2,7-metheno-1H-cyclopropa[b]naphthalen-1-yl)-; 50559-53-0; 3-(1a,2,7,7a-Tetrahydro-2-methoxy-8-phenyl-1,2,7-methenocyclopropa[b]naphthalen-1-yl)pyridine
EINECS	Contact for details

Quality Control

Every batch of this high-purity intermediate is manufactured and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical R&D and scale-up processes. Our quality commitment supports compliance with cGMP guidelines where required for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.