Description

2-Fluoro-6-Hydroxypyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a hydroxyl group on the pyridine ring, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Used to create specialized ligands for metal catalysis and asymmetric synthesis in fine chemical production.
• Material Science: Intermediate for synthesizing fluorinated polymers, liquid crystals, and electronic materials that require specific dielectric or optical properties.
• Chemical Research: Valuable reagent in academic and industrial R&D for exploring new reaction pathways and heterocyclic chemistry.
• Fluorine Chemistry: Serves as a model compound for studying the effects of fluorine substitution on the reactivity and physical properties of pyridine systems.

Basic Information

Product Name	2-Fluoro-6-Hydroxypyridine
CAS No.	50543-23-2
Molecular Formula	C5H4FNO
Molecular Weight	113.09 g/mol
Synonyms	6-Hydroxy-2-fluoropyridine; 2-Fluoro-6-pyridinol; 2-Fluoropyridin-6-ol; 2-Fluoro-6-hydroxypyridine; 6-Fluoro-2-pyridinol; 2-Fluoro-6-pyridinone (tautomer); 6-Fluoro-2(1H)-pyridinone
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-Hydroxypyridine is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.