Description

3-Chloro-4-Fluorophenyl Isocyanate is a versatile aromatic isocyanate building block used in the synthesis of advanced chemical intermediates. This compound is critical for introducing the 3-chloro-4-fluorophenyl moiety into larger molecular structures, enabling the development of compounds with specific biological or material properties. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the chloro-fluorophenyl group contributes to efficacy and selectivity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialty polyurethanes and polyurea coatings with enhanced chemical resistance.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and other functional materials requiring specific aromatic isocyanate components.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic pathways and creating novel heterocyclic compounds.

Basic Information

Product Name	3-Chloro-4-Fluorophenyl Isocyanate
CAS No.	50529-33-4
Molecular Formula	C7H3ClFNO
Molecular Weight	171.56 g/mol
Synonyms	1-Chloro-2-fluoro-4-isocyanatobenzene; 4-Fluoro-3-chlorophenyl isocyanate; (3-Chloro-4-fluorophenyl)isocyanate; Isocyanic acid, 3-chloro-4-fluorophenyl ester; 3-Chloro-4-fluoro-1-isocyanatobenzene; 3-Chloro-4-fluorobenzene isocyanate
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorophenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including assay by HPLC and impurity profiling, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.