Description

2-Chloro-5-(Trifluoromethyl)Phenyl Isocyanate is a versatile and highly reactive aromatic isocyanate building block. Its value lies in its ability to introduce both a chloro and a trifluoromethyl-substituted phenyl urea or carbamate moiety into target molecules, which is critical for modifying physical, chemical, and biological properties. This compound is primarily needed by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for synthesizing advanced intermediates, active ingredients, and functional materials.

Application

• Agrochemical Intermediate: Key building block for the synthesis of modern herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly in creating urea-based compounds with targeted biological activity.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the production of specialized polyurethanes and polyurea coatings with unique chemical resistance and durability.
• Chemical Synthesis: Employed as a reagent for introducing the phenyl isocyanate group in multi-step organic syntheses for fine chemicals and advanced materials.
• Ligand and Sensor Development: Useful in creating novel chemical sensors or metal-organic frameworks (MOFs) due to its reactive isocyanate group and distinct substitution pattern.

Basic Information

Item	Detail
Product Name	2-Chloro-5-(Trifluoromethyl)Phenyl Isocyanate
CAS No.	50528-86-4
Molecular Formula	C8H3ClF3NO
Molecular Weight	221.56 g/mol
Synonyms	1-Chloro-2-isocyanato-4-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluoro-p-tolyl isocyanate; 2-Chloro-α,α,α-trifluoro-p-phenylene isocyanate; 2-Chloro-5-(trifluoromethyl)benzenisocyanate; Isocyanic acid, 2-chloro-5-(trifluoromethyl)phenyl ester; 2-Chloro-5-trifluoromethylphenyl isocyanate
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Trifluoromethyl)Phenyl Isocyanate is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and polymerization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.