Description

2,4,6-Trifluorophenyl Isocyanate is a specialized aromatic isocyanate monomer featuring a trifluoromethyl-substituted phenyl ring. This compound is valued for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique fluorine substitution pattern imparts desirable properties like enhanced stability and lipophilicity. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Specialty Polymer Production: Serves as a monomer for creating polyurethanes and polyurea coatings with enhanced chemical resistance, weatherability, and low surface energy.
• Liquid Crystal & OLED Materials: Incorporated into the core structure of electronic display materials to modify dielectric constant and improve performance.
• Cross-linking Agent: Functions as an efficient cross-linker for polymers and resins, improving thermal and mechanical properties in advanced composites.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reactions in organofluorine chemistry and isocyanate-based transformations.

Basic Information

Product Name	2,4,6-Trifluorophenyl Isocyanate
CAS No.	50528-80-8
Molecular Formula	C7H2F3NO
Molecular Weight	173.09 g/mol
Synonyms	2,4,6-Trifluorophenyl isocyanate; Isocyanic Acid, 2,4,6-Trifluorophenyl Ester; 2,4,6-Trifluorobenzene Isocyanate; 1-Isocyanato-2,4,6-trifluorobenzene; α,α,α-Trifluoroisocyanatobenzene; NSC 405124; 2,4,6-Trifluorphenylisocyanat (German)
EINECS	Contact for details

Quality Control

Every batch of 2,4,6-Trifluorophenyl Isocyanate is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency that meets the exacting standards for pharmaceutical and advanced material synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its moisture-sensitive (hygroscopic) nature, the container must be kept tightly sealed under a dry inert atmosphere (e.g., nitrogen or argon) to prevent degradation by hydrolysis. Keep away from heat, open flames, and incompatible materials such as alcohols, amines, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.