Description

Methyl 2-Isocyanatothiophene-3-Carboxylate(Saltdata: Free) is a versatile and highly reactive heterocyclic building block used in advanced organic synthesis. Its core value lies in its dual functionality, combining a reactive isocyanate group with a thiophene carboxylic ester, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients, particularly in medicinal chemistry for drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiophene moiety can contribute to specific biological activity and photostability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers, such as polyurethanes and polyamides, with unique properties derived from the thiophene ring.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions, heterocyclic chemistry, and the development of novel synthetic methodologies.
• Ligand & Catalyst Development: Useful for constructing complex ligands for metal catalysis or as a precursor for functional materials used in electronic and optoelectronic applications.

Basic Information

Product Name	Methyl 2-Isocyanatothiophene-3-Carboxylate(Saltdata: Free)
CAS No.	50502-27-7
Molecular Formula	C7H5NO3S
Molecular Weight	183.18 g/mol
Synonyms	Methyl 2-isocyanato-3-thiophenecarboxylate; 3-Thiophenecarboxylic acid, 2-isocyanato-, methyl ester; 2-Isocyanato-3-thiophenecarboxylic acid methyl ester; Methyl 2-isocyanatothiophene-3-carboxylate; Methyl 3-thiophenecarboxylate-2-isocyanate; Thiophene-3-carboxylic acid, 2-isocyanato-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Isocyanatothiophene-3-Carboxylate(Saltdata: Free) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.