Description

Ethyl 4-Chloro-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by pharmaceutical R&D laboratories, agrochemical manufacturers, and fine chemical synthesis companies for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides and pesticides with specific modes of action.
• Chemical Biology: Serves as a core scaffold for designing molecular probes and enzyme inhibitors in drug discovery.
• Organic Synthesis: A versatile precursor for further functionalization via cross-coupling, hydrolysis, or amidation reactions.
• Material Science Research: Potential precursor for the development of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	Ethyl 4-Chloro-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate
CAS No.	50476-72-7
Molecular Formula	C9H8ClN3O2
Molecular Weight	225.63 g/mol
Synonyms	4-Chloro-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester; Ethyl 4-chloro-1H-pyrazolo[3,4-b]pyridine-5-carboxylate; 1H-Pyrazolo[3,4-b]pyridine-5-carboxylic acid, 4-chloro-, ethyl ester; 4-Chloro-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester; 50476-72-7; Ethyl 4-chloro-1H-pyrazolo[3,4-b]pyridin-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-1H-Pyrazolo[3,4-B]Pyridine-5-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.