Description

Tocofibrate is a synthetic chemical compound that combines structural elements of tocopherol (vitamin E) and clofibrate, a known lipid-modifying agent. This unique molecular design is engineered to leverage the antioxidant properties of tocopherol with the lipid-regulating activity of fibrates. It is primarily utilized in advanced pharmaceutical research and development, particularly in the study of metabolic disorders and cardiovascular health. Researchers and manufacturers in the pharmaceutical and nutraceutical sectors seek this compound for its potential application in novel therapeutic formulations.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced active pharmaceutical ingredients (APIs) targeting dyslipidemia.
• Biomedical Research: Used in in vitro and preclinical studies to investigate mechanisms of action related to lipid metabolism and oxidative stress.
• Nutraceutical Development: Explored as a potential component in advanced dietary supplements aimed at supporting cardiovascular wellness.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Metabolic Syndrome Studies: A research tool for exploring therapeutic interventions for conditions involving insulin resistance and abnormal lipid profiles.

Basic Information

Product Name	Tocofibrate
CAS No.	50465-39-9
Molecular Formula	C33H48O4
Molecular Weight	508.74 g/mol
Synonyms	2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl 2-(4-Chlorophenoxy)-2-methylpropionate; Tocofibrate; Vitamin E Clofibrate; (±)-α-Tocopheryl Clofibate; DL-α-Tocopheryl Clofibrate; Tocopherol Clofibrate Ester
EINECS	Contact for details

Quality Control

Our Tocofibrate is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and determination of residual solvents, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.