Description

n-[(Benzyloxy)Carbonyl]-L-Tyrosine 2,4,5-Trichlorophenyl Ester is a protected tyrosine derivative widely used as a key synthetic intermediate in peptide chemistry. This compound is essential for researchers and manufacturers requiring high-purity building blocks for the controlled synthesis of complex peptides and peptidomimetics. It is primarily utilized in pharmaceutical R&D, academic research, and the production of active pharmaceutical ingredients (APIs) where precise molecular assembly is critical.

Application

• Peptide Synthesis: Serves as a crucial tyrosine-protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Used in the development and scale-up of novel peptide-based therapeutics and drug candidates.
• Bioconjugation: Acts as a reagent for introducing tyrosine moieties into biomolecules for labeling or functionalization studies.
• Chemical Biology: Employed in the synthesis of peptide probes and tools for studying protein-protein interactions and enzyme activity.
• API Manufacturing: Functions as a building block in the industrial-scale production of specific peptide active pharmaceutical ingredients.
• Academic & Contract Research: A standard reagent in university laboratories and CROs (Contract Research Organizations) focused on organic and medicinal chemistry.

Basic Information

Product Name	n-[(Benzyloxy)Carbonyl]-L-Tyrosine 2,4,5-Trichlorophenyl Ester
CAS No.	50444-36-5
Molecular Formula	C23H18Cl3NO5
Molecular Weight	498.75 g/mol
Synonyms	Z-Tyr(2,4,5-Cl3-OPh)-OH; N-Cbz-L-Tyrosine 2,4,5-Trichlorophenyl Ester; Nα-Carbobenzoxy-L-tyrosine 2,4,5-trichlorophenyl ester; CBZ-L-Tyrosine 2,4,5-Trichlorophenyl Ester; (S)-2-(((Benzyloxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid 2,4,5-trichlorophenyl ester; N-Benzyloxycarbonyl-L-tyrosine 2,4,5-trichlorophenyl ester; Z-L-Tyrosine 2,4,5-Trichlorophenyl Ester
EINECS	Contact for details

Quality Control

Our n-[(Benzyloxy)Carbonyl]-L-Tyrosine 2,4,5-Trichlorophenyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research and synthesis applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	Contact for details
Melting Point	Contact for details
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm
Single Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.