Description

4-Hydroxyethynylestradiol is a synthetic, steroidal estrogen derivative of significant interest in pharmaceutical research and development. Its unique structural modifications make it a valuable intermediate for creating novel therapeutic agents targeting hormone-related pathways. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of advanced endocrine therapies and diagnostic tools. Its precise chemical profile enables critical studies in biochemistry and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and hormone analogs.
• Biochemical Research: Used as a reference standard or probe in studies of estrogen receptor binding and signal transduction mechanisms.
• Medicinal Chemistry: Serves as a core structure for the design and optimization of new chemical entities with potential therapeutic activity.
• Academic Research: Employed in university and institutional labs for fundamental studies in endocrinology and steroid metabolism.
• Reference Material: Used in analytical laboratories for method development and validation in the quantification of steroidal compounds.

Basic Information

Product Name	4-Hydroxyethynylestradiol
CAS No.	50394-90-6
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	17α-Ethynyl-4-hydroxyestra-1,3,5(10)-trien-3,17β-diol; 4-Hydroxy-17α-ethynylestradiol; 17α-Ethynyl-4-hydroxy-1,3,5(10)-estratriene-3,17β-diol; 4-Hydroxyethynyl oestradiol; 4-OH-EE2; 4-Hydroxy EE2
EINECS	Contact for details

Quality Control

Our 4-Hydroxyethynylestradiol is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. The product undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.