Description

2-Hydroxyethynylestradiol is a synthetic steroidal estrogen derivative, a key intermediate in advanced pharmaceutical research and development. This compound is valued for its structural specificity, enabling the synthesis of novel therapeutic agents targeting hormone-related pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of endocrine therapies and specialized chemical probes.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Endocrinology Research: Used as a reference standard or precursor in biochemical studies of estrogen receptor activity and hormone signaling.
• Chemical Synthesis: Serves as a specialized starting material for the preparation of labeled compounds or structurally modified estrogen analogs.
• Academic & Industrial R&D: Employed in discovery programs for developing targeted therapies in oncology, metabolic disorders, and reproductive health.

Basic Information

Product Name	2-Hydroxyethynylestradiol
CAS No.	50394-89-3
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	2-Hydroxyethynylestradiol; 17α-Ethynyl-2-hydroxyestra-1,3,5(10)-triene-3,17β-diol; 2-Hydroxy-17α-ethynylestradiol; 17α-Ethynyl-2-hydroxyestradiol; 2-OH-EE2; Estra-1,3,5(10)-triene-3,17β-diol, 17α-ethynyl-2-hydroxy-
EINECS	Contact for details

Quality Control

Our 2-Hydroxyethynylestradiol is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency. Quality is verified through comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.