Description

17-Hydroxy-17-Methyl-3-Oxospiro(Androst-5-Ene-4,1'-Cyclopropane)-2-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique steroidal spirocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing steroidal-based drugs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic compounds with targeted biological activity.
• Hormone Analog Development: Serves as a precursor in the research and development of modified steroid hormone analogs.
• Biochemical Research: Employed as a reference standard or probe in biochemical assays and metabolic pathway studies.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis for creating complex, high-value specialty chemicals.

Basic Information

Product Name	17-Hydroxy-17-Methyl-3-Oxospiro(Androst-5-Ene-4,1'-Cyclopropane)-2-Carbonitrile
CAS No.	50303-11-2
Molecular Formula	C23H31NO2
Molecular Weight	353.50 g/mol
Synonyms	17-Hydroxy-17-methyl-3-oxospiro[androst-5-ene-4,1'-cyclopropane]-2-carbonitrile; 2-Cyano-17-hydroxy-17-methyl-3-oxospiro[androst-5-ene-4,1'-cyclopropane]; Spiro[androst-5-ene-4,1'-cyclopropane]-2-carbonitrile, 17-hydroxy-17-methyl-3-oxo-; 50303-11-2; Androst-5-ene-2-carbonitrile, 17-hydroxy-17-methyl-3-oxospiro[4,1'-cyclopropane]-
EINECS	Contact for details

Quality Control

Our 17-Hydroxy-17-Methyl-3-Oxospiro(Androst-5-Ene-4,1'-Cyclopropane)-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.