Description

4-(3-(Trifluoromethyl)Phenyl)Pyridine is a high-value fluorinated aromatic heterocyclic compound, serving as a critical building block in advanced chemical synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethylphenyl group, which is essential for modulating the biological activity and physical characteristics of target molecules. This intermediate is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Serves as a versatile backbone for constructing nitrogen-containing ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as charge-transport layers and emitters for OLED devices.
• Fluorine Chemistry Studies: A valuable substrate for investigating structure-activity relationships (SAR) and the effects of fluorine substitution in medicinal chemistry.

Basic Information

Product Name	4-(3-(Trifluoromethyl)Phenyl)Pyridine
CAS No.	5957-98-2
Molecular Formula	C12H8F3N
Molecular Weight	223.20 g/mol
Synonyms	3'-(Trifluoromethyl)-[1,1'-biphenyl]-4-carbonitrile; 4-[3-(Trifluoromethyl)phenyl]pyridine; [1,1'-Biphenyl]-4-carbonitrile, 3'-(trifluoromethyl)-; 3-(Trifluoromethyl)-4-pyridinylbenzene; 4-(3-Trifluoromethylphenyl)pyridine; 4-(m-Trifluoromethylphenyl)pyridine; 3'-(Trifluoromethyl)biphenyl-4-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-(3-(Trifluoromethyl)Phenyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.