Description

4-(Trimethylsilyl)-3-Butyn-2-One is a versatile organosilicon building block featuring both a silyl-protected alkyne and a ketone functional group. This bifunctional nature makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring alkyne or ketone functionalization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the production of specialty polymers and silicon-based materials.
• Organic Synthesis Building Block: Employed in Sonogashira coupling, click chemistry, and other carbon-carbon bond-forming reactions in fine chemical production.
• Ligand and Catalyst Development: Utilized for the preparation of novel ligands and organometallic catalysts used in asymmetric synthesis.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and compound libraries.

Basic Information

Item	Details
Product Name	4-(Trimethylsilyl)-3-Butyn-2-One
CAS No.	5930-98-3
Molecular Formula	C7H12OSi
Molecular Weight	140.26 g/mol
Synonyms	3-Butyn-2-one, 4-(trimethylsilyl)-; Trimethylsilylacetylacetone; 4-Trimethylsilylbut-3-yn-2-one; 1-Trimethylsilyl-1-propyn-3-one; TMS-acetylene acetone; (Trimethylsilyl)acetylacetone; 3-Butyn-2-one, 4-(trimethylsilyl)-; 5930-98-3
EINECS	227-673-9

Quality Control

Our 4-(Trimethylsilyl)-3-Butyn-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.